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Explore evidence-based research on popular supplements, vitamins, and minerals. Every item is rated by the strength of its scientific evidence.

This page provides evidence-based research on popular supplements, helping you make informed decisions about your health and wellness. Each entry includes peer-reviewed evidence, UK-specific dosing guidance, warnings, and verified supplier comparisons.

Top Rated Supplements Based on Scientific Evidence

Strong Evidence

Creatine Monohydrate

The most effective ergogenic nutritional supplement currently available to athletes — ISSN Position Stand.

Strong Evidence

Vitamin D3

The sunshine vitamin — 1 in 5 UK adults are deficient, rising to 1 in 3 in winter.

Strong Evidence

Caffeine

The world's most popular stimulant — proven ergogenic aid.

Strong Evidence

Magnesium Glycinate

Highly bioavailable chelated magnesium — absorbed via dipeptide transport with minimal GI effects.

Vitamin C

Antioxidant powerhouse supporting immunity and collagen synthesis.

Strong Evidence

Omega-3 Fish Oil

Anti-inflammatory essential fats for heart, brain, and joint health.

All Items

Strong Evidence

Creatine Monohydrate

The most effective ergogenic nutritional supplement currently available to athletes — ISSN Position Stand.

Beta-Alanine

Buffers lactic acid to extend high-intensity endurance.

Strong Evidence

Caffeine

The world's most popular stimulant — proven ergogenic aid.

L-Citrulline

Boosts nitric oxide for better blood flow and exercise performance.

Strong Evidence

Whey Protein

Fast-digesting, leucine-rich complete protein — the most studied supplement for muscle protein synthesis.

Strong Evidence

Vitamin D3

The sunshine vitamin — 1 in 5 UK adults are deficient, rising to 1 in 3 in winter.

Strong Evidence

Vitamin B12

Essential for nerve function and red blood cell production.

Vitamin C

Antioxidant powerhouse supporting immunity and collagen synthesis.

Multivitamin

Daily nutritional insurance — useful for closing dietary gaps, but no proven benefit in well-fed healthy adults.

Vitamin K2

Directs calcium to bones and away from arteries.

Strong Evidence

Magnesium Glycinate

Highly bioavailable chelated magnesium — absorbed via dipeptide transport with minimal GI effects.

Zinc

Essential trace mineral for immunity, testosterone, and wound healing.

Iron

Critical for oxygen transport — but only supplement if deficient.

Strong Evidence

Omega-3 Fish Oil

Anti-inflammatory essential fats for heart, brain, and joint health.

Ashwagandha

Adaptogenic herb for stress reduction and hormonal balance.

Probiotics

Live bacteria to support gut health and immune function.

Collagen

Structural protein for skin elasticity, joint comfort, and hair health.

Turmeric & Curcumin

Polyphenol with promising joint-pain evidence — but raw turmeric is poorly absorbed.

Coenzyme Q10

Mitochondrial cofactor — best evidence is for statin-associated muscle symptoms and heart failure.

Lion's Mane

Edible mushroom with preliminary cognitive evidence — too early to call.